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In multicellular organisms, inflammation is the main host defense response to tissue harm, infectious agents or autoimmune responses, and can also be a crucial component of your immune reaction. Symptoms of inflammation incorporate swelling, redness with the skin, and suffering. It could be acute or Long-term determined by time and pathological features.one zero one In recent years, reports on benzofuran derivatives have found that person derivatives have good anti-inflammatory exercise. The Main compound two-acetylbenzofuran was synthesized by coupling 3-(trifluoromethyl) phenyl diazo chloride with salicylaldehyde.

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Alcohols and phenols can also be examined as the probable radical precursors for this transformation. Even so, none of these gave the desired benzofuran products.

make intermediate B. The intermediate B even more underwent intramolecular cyclization accompanied by the elimination

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